Pathology

Embedding station.
Histotechnologist Pat Wilcox, ASCP, embedding specimens for histology.

Comparative Pathology in Translational Science

Faculty, fellows, and residents in Comparative Pathology identify and investigate naturally occurring disease in our institutional animal colonies and collaborate in diverse research areas. Pathologists work with clinical veterinarians to diagnose conditions identified via routine colony health surveillance, and from our clinical veterinarians and investigators.  Pathologists perform complete gross and histopathologic examinations of animals or biopsies. 

Every case is formally reviewed by an ACVP board-certified veterinary pathologist. Final reports are sent to the investigator and entered into the computerized Comparative Pathology database: more than 68,000 archived cases are available at Johns Hopkins for research and review.

  • Our Comparative Pathology faculty also provide diagnostic support and conduct research collaborations with a number of regional institutions, including the National Aquarium, the National Zoo and the Maryland Zoo in Baltimore, all of which share a common interest in Comparative Pathology.  

Collaboration and Consultation

Consultation and collaboration for experimental design and pathology is available though Dr. Cory Brayton and the Phenotyping Core, or by contacting other comparative pathology faculty. Pathology consulting and research collaborations through the phenotyping core are customized to the research project and model, can include animal model selection, experimental design, test development, procedural training, specialized testing and pathology procedures, training, reporting, imaging, morphometry, manuscript and grant preparation, and involves relevant experts within and beyond our department.

 

Faculty

MCP anatomic pathology faculty are specialty board certified in the American College of Veterinary Pathologists (ACVP). They support, conduct and collaborate in translational biomedical science at JHU.

  • Joseph L. Mankowski, DVM, PhD, Dipl. ACVP
    Professor
    Interim Director, Molecular and Comparative Pathobiology
    More than 25 years of veterinary anatomic pathology experience
    Pathology Expertise: Primate pathology, neuropathology
    Research interests: Neuropathology, retrovirology
     
  • Chris Zink, DVM, PhD, Dipl. ACVP
    Professor
    More than 43 years of veterinary anatomic pathology experience
    Pathology Expertise: Primate pathology, neuropathology
    Research interests: Neuropathology, retrovirology
     
  • Cory Brayton, DVM, Dipl. ACLAM, Dipl. ACVP
    Associate Professor
    Director, Phenotyping Core
    More than 20 years experience in comparative medicine and pathology
    Pathology Expertise: Genetically engineered mice and other models
    Research Interests: Genetic (and epigenetic) mechanisms of aging, cancer, infectious disease, cardiovascular, digestive, musculoskeletal, neurologic disease
     
  • Kathleen Gabrielson, DVM, PhD, Dipl. ACVP
    Associate Professor
    More than 25 years of veterinary anatomic pathology experience
    Pathology expertise: Cardiac pathology, cancer
    Research Interests: Cardiovascular disease, cancer, pathology, toxicology, signal transduction, cancer therapy
  •  
  • Sarah E. Beck, DVM, PhD, Dipl. ACVP
    Assistant Professor
    More than 8 years of veterinary anatomic pathology experience
    Pathology expertise: Primate pathology, neuropathology, nonhuman primate and rodent models of HIV infection
    Research Interests: Retrovirology, viral immunology, cell-mediated immunity, neuropathology
     
  • Lisa M. Mangus, DVM, PhD, Dipl. ACVP
    Instructor
    More than 8 years of veterinary anatomic pathology experience
    Pathology expertise: Zoo and aquatic veterinary pathology, primate pathology, neuropathology
    Research Interests: Peripheral neuropathy, retrovirology, neuropathology, naturally occurring disease of zoo and aquatic species
  •  

  •