In Vivo Testing Services Available From The Phenotyping Core

The Phenotyping Core provides many services to support translational animal research at the Johns Hopkins University. Below is a list of those available and the relevant personnel to contact for further information. Please note that some large scale or intellectually-involved projects may merit grant support or collaboration of the participating faculty member. To officially schedule a service request, please use the iLAB System at JHU (note: JHED login is required). For terminal testing (necropsy and histology), please see our list of Research Pathology Services.

Behavioral Testing

Service
Contact
Fee
Notes

Clincal/Physical Exam: Includes SHIRPA-type evaluation of sensory and motor phenotypes.
Nadine Forbes McBean
$75 per hour.
Available cage-side or in the Phenotpying Core. Requires appropriate control animals. Training available.

Acoustic/Auditory Phenotyping: Assessment of hearing function in mice and rats.
Amanda Lauer
Varies, pleae enquire. Collaboration may be preferred or required.
Requires appropriate control animals.

Behavioral Assessment: Available for mice and rats.
Mikhail Pletnikov
Varies, pleae enquire. Collaboration may be preferred or required.
Requires appropriate control animals. Performed at the School of Medicine Behavior Core.

Request a service via the JHU iLAB System

Imaging and Metabolic Testing

Service
Contact
Fee
Notes

Body Composition: Quantification of body fat, lean mass, and water with an EchoMRI QNMR instrument.
Nadine Forbes McBean
$75 per hour.
Performed in the Core. Requires appropriate control animals.

Faxitron Radiography: High resolution “flat film” radiography for small rodents.
Nadine Forbes McBean
$75 per hour + $10 per film.
Performed in the Core. Films can be scanned for archival and analysis.

Cardiovascular Phenotyping: Imaging, ultrasound, blood pressure, and ECG tests for rodents.
Kathleen Gabrielson
Varies, pleae enquire. Collaboration may be preferred or required.
Tests performed in MRB facilities on live animals.

Advanced Imaging: MRI, PET, SPEC, CT, and IVIS imaging for rodents.
SAIRP
Varies, pleae enquire. Collaboration may be preferred or required.
Tests performed in MRB facilities on live animals or specimens.

Pulmonary Phenotyping: Plethismography and other pulmonary function tests.
Wayne Mitzner
Varies, pleae enquire. Collaboration may be preferred or required.
Tests performed on live animals.

Mass Spectrometry and Metabolomics: Screening for protein and small metabolit biomarkers.
David Graham
Varies, pleae enquire. Collaboration may be preferred or required.
Tests available for urine, plasma, and other specimens. See the Center for Resources in Integrative Biology for more details.

Metabolic Phenotyping: Includes calorimetry; O2, food, and water consumption; urinary and/or fecal output measurements.
Susan Aja
See the Centralized Services for Metabolism Research for more details.
Tests performed on live animals.

Pathogen Screening: Includes diagnostic serology, parasitology, microbiology, or PCR for animal pathogens.
Julie Watson
Varies, please enquire.
Please contact Research Animal Resources to report ill mice or other clinical problems.

Additonal Rodent Services: Includes breeding, genotyping, fostering, or special procedures.
Julie Watson
Varies, please enquire.
Please contact Research Animal Resources to report ill mice or other clinical problems.

Request a service via the JHU iLAB System