Postdoctoral Position in the Department of Pediatric Infectious Diseases: Molecular and Immunologic Mechanisms Behind HIV-1 Persistence in Young Persons Living with Perinatal HIV-1 Infection

Primary faculty: Dr. Deborah Persaud

A Postdoctoral position is available in the laboratory of Dr. Deborah Persaud, Professor of Pediatrics, Division of Infectious Diseases, Johns Hopkins University School of Medicine, and Department of Molecular Microbiology and Immunology, and International Health at the Bloomberg School of Public Health in Baltimore, MD.

Our research focuses on HIV remission and cure in infants, children, adolescents and young adults living with perinatal infection globally. We study the unique aspects of HIV infection arising from perinatal infections through investigation of molecular and cellular mechanisms of HIV persistence during long-term ART in order to inform novel treatments aimed at preventing HIV rebound off ART. Our studies of HIV persistence are primarily conducted in the context of novel therapeutics in clinical trials globally sponsored by the NIH-funded clinical trials (IMPAACT) Network, aimed at HIV remission and cure for this population.

The position includes the following research: understanding the dynamics of establishment and persistence of latent HIV-1 reservoirs in perinatal infections, defining the mechanisms of maintenance of these latent HIV reservoirs and those driving differences in propensity for latency reversal, and single-cell transcriptomics to probe innate and adaptive immune responses at play during early and very early treatment.

Applicants should hold a PhD degree and have a strong background in cellular and molecular biology or immunology. Experiences/skills in the following areas are desired: standard molecular and tissue culture techniques, and flow cytometric analyses. Capacity to multitask, as well as fluency in written and spoken English are required.

For those interested, please send a curriculum vitae, names and contact information (email and telephone numbers) of three references to Dr. Deborah Persaud (dpers@jhmi.edu) and Dr. Tang Dhummakupt (adhumma1@jhmi.edu). It is the policy of the School of Medicine that all postdocs, regardless of funding source shall be paid according to the NIH stipend scale. The salary will be based on this scale and commensurate with years of postgraduate training

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