Mechanisms underlying differential disease outcomes in progressive and natural hosts of SIV - One Medicine Molecular & Comparative Pathobiology Seminar Series

MCP Seminar
Nov 8, 2019 1:00pm

Darner Ross G007 conference room.  

On Friday, November 8th 2019, Dr. Janice Clements from the Department of Molecular and Comparative Pathobiology has invited Dr. J.C. Mudd to present at the department’s One Medicine seminar. 

This will be taking place from 1pm – 2pm in the Darner Ross G007 conference room. 

Dr. Mudd’s talk is titled: Mechanisms underlying differential disease outcomes in progressive and natural hosts of SIV

A brief bio of Dr. Mudd’s work:

My research has focused on understanding the pathogenesis of primate lentiviral infections. My aim is to use the knowledge gained through this research to develop novel therapeutic interventions for chronic human immunodeficiency virus (HIV) infection. As a senior postdoc in the laboratory of Jason Brenchley, I currently focus on nonhuman primate models of two lentiviral infections: progressive simian immunodeficiency virus (SIV) infection and nonprogressive SIV infections of natural host species. In the former setting, a major aspect of my work examines immunological dysfunction and microbial dysbiosis as it relates to breakdown of the gastrointestinal (GI) tract. In the latter setting, my work involves using systems- based approaches to identify mechanisms by which African green monkeys (AGMs) down-regulate CD4 to reduce target cell availability.

All are welcome to attend.

If you would be willing to post this seminar in your department please email me at woodland@jhmi.edu for the PDF.