ME:680.712 Phenotyping for Functional Genetics

Johns Hopkins Phenotyping

(and Mouse Pathobiology) Course(s)


NEXT SHORT COURSE: July 15-19, 2019 - contact us for information   
In addition, we are developing online modules for parts of this course.
Please complete this survey to help us build a better course. Its very short and we will appreciate your input!

This JHUSOM graduate school course is intended for graduate students or postdocs at any level, who currently work with, or expect to work with mouse models and genetically engineered mice. Since 2010 this has been offered in a short course format, largely for continuity of the practical laboratory training experience.

Up to 42 contact hours: 11.5hr Laboratory sessions;  24.5hr Lectures; 7 hr. poster sessions, laboratory tours, pathology slide conference.

Four (4) Hands-on Laboratory sessions (11.5 hours total)  include clinical and physical examination of mice, specimen collection, clinical pathology and anatomic pathology:

  • ONLY Students registered to take this course FOR CREDIT may participate in laboratory sessions.
  • Graduate students who AUDIT the course, also postdocs, faculty, staff, may wait list to participate in laboratory sessions if space is available. CONTACT to request to wait list.
  • Familiarity with basic anatomy is EXPECTED for participation in laboratory sessions.

Syllabus material is provided:   Hard copy laboratory manual is provided to all enrolled in laboratory sessions.  Lecture and laboratory syllabus material is provided electronically as pdf's linked to the program.   It is NOT necessary to purchase a text book.

Course credit and grades are based on:

  1. Attendance and participation in lecture and laboratory sessions  Monday morning through Friday noon, and
  2. Exam ('take home'), distributed Monday at the beginning of the course, and Due Friday, 5pm.  
    The exam is intended to be practical and relevant to diverse research areas.
  • Lectures in MRB Tilghman auditorium and in MRB  G01.
  • Exhibits, Poster session, Reception in MRB Turner Concourse (Monday, Tuesday).
  • Laboratory sessions (4 sessions ~10 hr total) in PCTB.

Faculty from JHU School of Medicine and Bloomberg School of Public Health introduce students to mouse handling, biology, pathology, genetics, normal 'phenotypes', phenotyping concepts, and to new and established phenotyping capabilities in multiple disciplines.  JHU cores and resources are highlighted. See previous course programs/schedules below.

Topics include mouse genetics and 'normal' phenotypes, genetic engineering strategies for mice (and other animals), traditional and novel imaging strategies, various aspects of neurobehavioral phenotyping, metabolic phenotyping, pulmonary phenotyping, clinical pathology and anatomic pathology phenotyping.  

Course Co-Directors: Cory Brayton, DVM, Dip. ACLAM, ACVP, Julie Watson, MA, VetMB, Dip ACLAM, Kinta Diven, MS.

Laboratory Coordinator: Nadine Forbes McBean, MS -

Course Administrator: Wendy Elza - - 410 502 3050
Graduate students and postdocs in JHU institutions OTHER THAN SOM should contact Wendy for assistance.