Extracellular Vesicles

Extracellular Vesicles

Extracellular vesicles (EVs), also known as “exosomes” and “microvesicles,” are small cellular packets released from all known cell types that serve as intracellular messengers. EVs are widely hailed as promising theranostics: diagnosis and prognosis, since they can be traced back to cells of origin, and in therapies, where EVs might initiate signaling or delivery bioactive molecules in a cell-specific manner. MCP has an active EV research program investigating how EVs modulate cellular process such as RNA regulation. Funded projects focus on EVs in drug abuse, HIV disease, Alzheimer’s Disease, and the gastrointestinal tract. We also collaborate with internal and external researchers on studies of psychiatric diseases, thyroid cancer, stem cell therapies, cardiac disease, and infectious diseases, among others.